J. L. Syrjänen‡, A Nore, E Roselletti, T Chakraborty, R. L. Perera, D. Wilson‡. Structural insights into mechanisms of zinc scavenging by the Candida albicans zincophore Pra1. (2025) bioRxiv 2025.01.09.632233; doi: https://doi.org/10.1101/2025.01.09.632233. ‡co-corresponding
Syrjänen JL , Epstein M , Gómez R , Furukawa H. Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red. (2023) Nat Commun.2023 Jun 28; 14(1):3821. doi:10.1038/s41467-023039388-3. PMID: 37380652 PMCID: PMC10307800
Syrjänen JL, Michalski K, Chou TH, Grant T, Rao S, Simorowski N, Tucker SJ, Grigorieff N, Furukawa H. (2020) Structure and assembly of calcium homeostasis modulator proteins. Nat Struct Mol Biol. 2020 Jan 27 (2):150-159. doi: 10.1038/s41594-019-0369-9.
Michalski K*, Syrjänen JL*, Henze E, Kumpf J, Furukawa H, Kawate T (2020) The cryo-EM structure of a pannexin 1 reveals unique motifs for ion selection and inhibition. Elife.2020;9:e54670 doi: 10.7554/eLife.546 *co-first author
M. R. Dyson, E. Masters, D. Pazeraitis, R. L. Perera, J. L. Syrjänen, S. Surade, N. Thorsteinson, K. Parthiban, P. C. Jones, M. Sattar, G. Wozniak-Knopp, F. Rueker, R. Leah, J. McCafferty. Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries. MAbs. 12 (2020), doi:10.1080/19420862.2020.1829335.
J. L. Syrjänen*, I. Heller*, A. Candelli, O. R. Davies, E. J. G. Peterman, G. J. L. Wuite, L. Pellegrini. Single-Molecule observation of DNA compaction by meiotic protein SYCP3. Elife. 6 (2017), doi:10.7554/eLife.22582. *co-first author
K. J. Bandyra, D. Sinha, J.L. Syrjänen, B. F. Luisi, N. R. De Lay. The ribonuclease polynucleotide phosphorylase can interact with small regulatory RNAs in both protective and degradative modes. RNA. 22(2016), doi:10.1261/rna.052886.115.
J. L. Syrjänen, L. Pellegrini, O. R. Davies, A molecular model for the role of SYCP3 in meiotic chromosome organisation. Elife. 3 (2014), doi:10.7554/eLife.02963.
Syrjänen, JL*, Michalski K*, Kawate, T. & Furukawa, H. On the molecular nature of large-pore channels. (2021) Journal of Molecular Biology. 2021 Aug 20;433(17):166994. doi: 10.1016/j.jmb.2021.166994. Epub 2021 Apr 16.
J. McCafferty, R Perera, M.R. Dyson, K Partibhan, J.L. Syrjänen. Selecting for developability of polypeptide drugs in eukaryotic cell display systems. US11499150B2 (granted 2022)